The best human growth hormone (HGH) injections are those which undergo strict quality control by regulatory bodies and have been approved by the FDA as safe and effective.
All such HGH injections are legal in the US and contain the same active ingredient – somatropin. Yet, the different brands may vary in regard to price, cost-effectiveness, ease of use, transportation, and storage requirements.
Furthermore, all growth hormone injections are prescription medications. Thus, the only effective and safe way to obtain any of the best HGH injections is to first visit a medical doctor who can evaluate your condition and prescribe appropriate treatment.
If you have the medical indications, your physician will prescribe you one of the FDA-approved brands and control your dosage to ensure effectiveness while minimizing the risk of adverse reactions.
Taking genuine HGH will also help to prevent side effects that illegal but cheaper alternatives may cause due to potential impurities, toxins, and even pathogens.
What is the best HGH on the market?
Currently, the best form of HGH on the market (and the only form of HGH that’s approved by the FDA) is a recombinant human growth hormone called somatropin.
Somatropin is highly effective for patients suffering from growth hormone deficiency (GHD) because it has an identical structure to the HGH that’s naturally produced by the human pituitary gland. Yet, it is effective only when administered via injections.
There are several brands of HGH that the FDA has approved for prescription, distribution and medical use in the US. These brands and their corresponding manufacturers include:
- Norditropin HGH by Novo Nordisk, Denmark
- Nutropin by Genentech, US
- Humatrope by Eli Lilly, US
- Genotropin HGH by Pfizer, US
- Zomacton by Ferring, Switzerland
- Saizen by EMD Serono, Germany
- Omnitrope by Sandoz, Germany
The companies with the largest market shares in the US and globally are Novo Nordisk, Pfizer, Eli Lilly, and EMD Serono. Novo Nordisk is the leader amongst them as Norditropin is accounting for more than 30% of the HGH injections sold worldwide.
In the US, as well as globally, Norditropin is also the most commonly prescribed brand of HGH injections. Growth hormone can be prescribed for several medical indications which include growth failure in children (including due to GHD), GHD in adults, muscle-wasting due to AIDS (loss of more than 10% of body weight), and short-bowel syndrome (SBS).
Why injections are the best form of HGH?
Injections are the best form of HGH because they provide the only reliable method to administer the growth hormone in the human body successfully and increase serum HGH concentrations.
|Feature||HGH Injections||HGH Pills||HGH Gels||HGH Nasal Spray|
|Bioavailability||High bioavailability||No absorption - destroyed in the digestive system||No absorption through the skin||Low bioavailability|
|Effectiveness||Supported as effective by extensive research||None due to lack of absorption||None due to lack of absorption||Has not been investigated yet|
|Safety||Supported as safe by extensive research||Has not been investigated yet||Has not been investigated yet||Has not been investigated yet|
All legal HGH injections contain a recombinant form of the growth hormone. This is a hormone produced by recombinant DNA technology, which involves genetically modified strains of the bacteria Escherichia coli.
During fermentation, the bacteria produces a protein that contains 192 amino acids. The scientists then remove the terminal amino acid methionine, obtaining the molecule of HGH which has 191 amino acids.
Since it has the same structure as natural growth hormone, there is no risk of triggering allergic reactions or other unwanted effects when HGH is used in physiologic doses.
HGH injections are suitable for all patients except those with contraindications for subcutaneous injections such as patients with coagulation problems
Furthermore, individuals with allergies to some of the preservatives commonly found in the diluents for HGH injections can replace them with sterile water and inject the product safely.
It’s important to note that even the best HGH injections may take some time to work. Serum GH levels increase immediately after injection but it usually takes at least 4 weeks of HGH therapy results to appear.
The effectiveness of other forms of HGH such as nasal sprays and when they may occur haven’t been investigated yet by studies with sufficient length.
Growth hormone injections should be given subcutaneously, as the method increases the half-life of the medication and helps mimic the natural diurnal changes in GH levels.
What is the most effective brand of HGH?
All FDA-approved HGH brands are equally effective as they have the same ingredients. Therefore, patients should select the most suitable HGH product according to their needs, personal preferences, and the affordability of the brand. Whether the product is covered or not by your insurance provider may also influence your choice.
All brands of HGH are equally effective for stimulating muscle protein synthesis, increasing lean mass, and body fat loss
Yet, some brands of HGH such as Zorbtive manufactured by EMD Serono have been FDA-approved specifically for short bowel syndrome, while Serostim which is produced by the same manufacturer is approved for both SBS and AIDS-related muscle wasting.
The easiest to use for beginners
Norditropin is arguably the best and easiest one to use since it comes as an all-in-one device called the Norditropin FlexPro Pen. HGH in the injection pen is already reconstituted into a liquid and prefilled. This means there is no need to use syringes or replace cartridges.
What is more, the solution is already preloaded, which means that all you have to do is prime it (check the flow through the pen and the needle) before your first use and then simply replace the needle before every next injection.
The downside is that you cannot change and refill the cartridge of the pen once it is empty, so you must discard the whole device and get a new one, ultimately increasing the monthly costs.
The most convenient for storage and transportation
Norditropin FlexPro Pen and Genotropin Miniquicks are both great options for those who prefer mobility and easy storage. They come in prefilled pens that do not require you to carry syringes.
Unlike most other HGH products, Norditropin FlexPro Pen can be stored at room temperature even after the first use. You can store it at room temperature for 21 days after your first injection.
In comparison, most other pens, cartridges, and vials need to be refrigerated and shouldn’t be stored at room temperature for more than 30 minutes per day.
Genotropin Miniquicks are single-use devices that contain 2 cartridges – one with the HGH in powdered form and the other one with a preservative-free diluent. This allows for safe storage at room temperature for up to 3 months.
Once the two cartridges are mixed, the Miniquick pen must be used within 24 hours. The lack of preservatives in the diluent also makes the product suitable for those with allergies.
The most affordable brands of HGH
HGH brands such as Omnitrope and Humatrope which offer growth hormone in vials usually come at a much lower cost than the formulations in injection pens or similar devices.
For example, the cost of a 5.8 mg vial of Omnitrope is less than $600, and depending on the dose it can be sufficient for up to a month of therapy. Therefore, your monthly price would be less than half of what you would pay when using injection pens.
Injection pens with replaceable cartridges may also have a higher waste percentage
Yet, you should keep in mind that using vials and syringes to manually reconstitute the HGH with a diluent and then inject it often leads to some of the product going to waste. Studies report that about 23% of the HGH may go to waste when injecting growth hormone with regular syringes.
In comparison, the Norditropin FlexPro pen led to just 1% of the HGH going to waste.
Discover the cost of other HGH brands, what affects the price and why you should not choose cheaper but illegal options.
Dangers of fake and illegal HGH brands
Unfortunately, HGH injections are often faked or imported illegally from other countries which lack the quality regulations in the US. That’s usually done by companies operating from overseas in an attempt to lure buyers with lower prices and less purchase requirements.
For example, some of the most common illegal HGH injections which are imported from overseas are Jintropin, which is manufactured in China, and Hygetropin which is manufactured somewhere in India.
These brands are not FDA-approved and do not undergo the same quality monitoring or regulations as the leading HGH manufacturers
Therefore, there is a considerable risk that such products may have expired, may not contain any HGH, or worse – may contain impurities and toxins which may put your health at risk.
In addition, there are many counterfeit products manufactured in Mexico and China, which carry the same names as some of the leading HGH brands. For example, authorities have issued warnings about fake Serostim, Nutropin, and others.
The dangers when taking these products are once again potential ineffectiveness, presence of impurities, toxins, and pathogens.
The most attractive feature of all these illegal and counterfeit products is the considerably lower cost and the opportunity to purchase them without a prescription.
Compared to FDA-approved brands, these growth hormone injections come at prices that are 2-3 times lower.
Considering that, we strongly advise against saving money while risking your health by injecting yourself with unregulated and illegal substances.
Get a free consultation with our medical expert for any questions about hormone replacement therapy